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[Phosphoramidites]Alkyne Phosphoramidite, 5

Alkyne Phosphoramidite, 5'-terminal

订购货号产品名称及规格价格(￥)

22260Alkyne Phosphoramidite, 5'-terminal, 250 mg2990.00

42260Alkyne Phosphoramidite, 5'-terminal, 1 g5850.00

62260Alkyne Phosphoramidite, 5'-terminal, 5 g25870.00

Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry.

This alkyne amidite has several advantages over 5’-hexynyl phosphoramidite, 5'-butynyl-CEP, and other 5'-terminal alkyne phosphoramidites. First, it is solid compound which is easier to handle and dispense. And due to its structure, it is also more stable in solution, and has longer shelf life

Diluent for this phosphoramidite is acetonitrile, 5 min coupling time is recommended. Because this amidite does not contain 5'-terminal DMT group, no 5'-deprotection needed. Oligonucleotides should be deblocked under standard conditions, and purified by PAGE, or ion exchange HPLC.

Oligonucleotides with this modification are ideal for the use in Click Chemistry (see our recommended protocol).

相关产品：

Alkyne Amidite, hydroxyprolinol - alkyne phosphoramidite with DMT group for cartridge and HPLC purification

General properties

Appearance: colorless solid

Molecular weight: 409.50

Molecular formula: C21H36N3O3P

Solubility: good in acetonitrile and dichloromethane

Quality control: NMR 1H (95%), 13C, and 31P, TLC, functional testing

Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

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